Nkx2.5 regulates Endothelin Converting Enzyme-1 during pharyngeal arch patterning

In gnathostomes, dorsoventral (D-V) patterning of neural crest cells (NCC) within the pharyngeal arches is crucial for the development of hinged jaws. One of the key signals that mediates this process is Endothelin-1 (EDN1). Loss of EDN1 binding to the Endothelin-A receptor (EDNRA) results in loss o...

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發表在:Genesis
Main Authors: Iklé, Jennifer M., Tavares, Andre L. P., King, Marisol, Ding, Hailei, Colombo, Sophie, Firulli, Beth A., Firulli, Anthony B., Targoff, Kimara L., Yelon, Deborah, Clouthier, David E.
格式: Artigo
語言:Inglês
出版: 2017
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5364067/
https://ncbi.nlm.nih.gov/pubmed/28109039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvg.23021
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