Chlamydia interfere with an interaction between the mannose-6-phosphate receptor and sorting nexins to counteract host restriction

Chlamydia trachomatis is an obligate intracellular pathogen that resides in a membrane-bound compartment, the inclusion. The bacteria secrete a unique class of proteins, Incs, which insert into the inclusion membrane and modulate the host-bacterium interface. We previously reported that IncE binds s...

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Pubblicato in:eLife
Autori principali: Elwell, Cherilyn A, Czudnochowski, Nadine, von Dollen, John, Johnson, Jeffrey R, Nakagawa, Rachel, Mirrashidi, Kathleen, Krogan, Nevan J, Engel, Joanne N, Rosenberg, Oren S
Natura: Artigo
Lingua:Inglês
Pubblicazione: eLife Sciences Publications, Ltd 2017
Soggetti:
Biophysics and Structural Biology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5364026/
https://ncbi.nlm.nih.gov/pubmed/28252385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.22709
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