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Metformin inhibits gastric cancer cells metastatic traits through suppression of epithelial-mesenchymal transition in a glucose-independent manner

Epithelial-mesenchymal transition (EMT), which is mainly recognized by upregulation of mesenchymal markers and movement of cells, is a critical stage occurred during embryo development and spreading cancerous cells. Metformin is an antidiabetic drug used in treatment of type 2 diabetes. EMT inhibito...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Valaee, Shiva, Yaghoobi, Mohammad Mehdi, Shamsara, Mehdi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5363973/
https://ncbi.nlm.nih.gov/pubmed/28334027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0174486
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