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Mutations that increase the activity of a transcriptional activator in yeast and mammalian cells.

Activating region I of GAL4 protein is a stretch of amino acids, positioned adjacent to the DNA-binding region, that activates transcription in yeast and, as we show here, in mammalian cells. Here we describe mutations located throughout a 65-amino acid region that increase the activation function o...

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Sonraí bibleagrafaíochta
Foilsithe in:Proc Natl Acad Sci U S A
Príomhchruthaitheoirí: Gill, G, Sadowski, I, Ptashne, M
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: National Academy of Sciences 1990
Ábhair:
Rochtain ar líne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC53639/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2179950/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.6.2127
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