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Evaluating alignment and variant-calling software for mutation identification in C. elegans by whole-genome sequencing
Whole-genome sequencing is a powerful tool for analyzing genetic variation on a global scale. One particularly useful application is the identification of mutations obtained by classical phenotypic screens in model species. Sequence data from the mutant strain is aligned to the reference genome, and...
Enregistré dans:
| Publié dans: | PLoS One |
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| Auteurs principaux: | , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Public Library of Science
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5363872/ https://ncbi.nlm.nih.gov/pubmed/28333980 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0174446 |
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