Targeted deep sequencing of plasma circulating cell-free DNA reveals Vimentin and Fibulin 1 as potential epigenetic biomarkers for hepatocellular carcinoma

Hepatocellular carcinoma (HCC) is the second most common cause of cancer death worldwide, but is still lacking sensitive and specific biomarkers for early diagnosis and prognosis. In this study, we applied targeted massively parallel semiconductor sequencing to assess methylation on a panel of genes...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Holmila, Reetta, Sklias, Athena, Muller, David C., Degli Esposti, Davide, Guilloreau, Paule, Mckay, James, Sangrajrang, Suleeporn, Srivatanakul, Petcharin, Hainaut, Pierre, Merle, Philippe, Herceg, Zdenko, Nogueira da Costa, Andre
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5363871/
https://ncbi.nlm.nih.gov/pubmed/28333958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0174265
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