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Dynamic Regulation of Homer Binding to Group I Metabotropic Glutamate Receptors by Preso1 and Converging Kinase Cascades

In rat sympathetic neurons from the superior cervical ganglia (SCG) expressing metabotropic glutamate receptor mGluR1 or mGluR5, overexpression of scaffolding Homer proteins, which bind to a Homer ligand in their C termini, cause receptor clustering and uncoupling from ion channel modulation. In the...

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Detalhes bibliográficos
Publicado no:J Pharmacol Exp Ther
Main Authors: Hu, Jia-Hua, Worley, Paul F., Kammermeier, Paul J.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5363770/
https://ncbi.nlm.nih.gov/pubmed/28179473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.116.238394
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