Impact of Nonalcoholic Fatty Liver Disease on Toxicokinetics of Tetrachloroethylene in Mice

Lifestyle factors and chronic pathologic states are important contributors to interindividual variability in susceptibility to xenobiotic-induced toxicity. Nonalcoholic fatty liver disease (NAFLD) is an increasingly prevalent condition that can dramatically affect chemical metabolism. We examined th...

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Udgivet i:J Pharmacol Exp Ther
Main Authors: Cichocki, Joseph A., Furuya, Shinji, Konganti, Kranti, Luo, Yu-Syuan, McDonald, Thomas J., Iwata, Yasuhiro, Chiu, Weihsueh A., Threadgill, David W., Pogribny, Igor P., Rusyn, Ivan
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Pharmacology and Experimental Therapeutics 2017
Fag:
Metabolism, Transport, and Pharmacogenomics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5363767/
https://ncbi.nlm.nih.gov/pubmed/28148637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.116.238790
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