Oncolytic Adenoviruses Armed with Tumor Necrosis Factor Alpha and Interleukin-2 Enable Successful Adoptive Cell Therapy

Adoptive cell therapy holds much promise in the treatment of cancer but results in solid tumors have been modest. The notable exception is tumor-infiltrating lymphocyte (TIL) therapy of melanoma, but this approach only works with high-dose preconditioning chemotherapy and systemic interleukin (IL)-2...

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Publicat a:Mol Ther Oncolytics
Autors principals: Havunen, Riikka, Siurala, Mikko, Sorsa, Suvi, Grönberg-Vähä-Koskela, Susanna, Behr, Michael, Tähtinen, Siri, Santos, João Manuel, Karell, Pauliina, Rusanen, Juuso, Nettelbeck, Dirk M., Ehrhardt, Anja, Kanerva, Anna, Hemminki, Akseli
Format: Artigo
Idioma:Inglês
Publicat: American Society of Gene & Cell Therapy 2016
Matèries:
Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5363700/
https://ncbi.nlm.nih.gov/pubmed/28345026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omto.2016.12.004
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