PDGF-CC underlies resistance to VEGF-A inhibition and combinatorial targeting of both suppresses pathological angiogenesis more efficiently

Anti-VEGF-A therapy has proven to be effective for many neovascular diseases. However, drug resistance to anti-VEGF-A treatment can develop. Also, not all patients with neovascular diseases are responsive to anti-VEGF-A treatment. The mechanisms underlying these important issues remain unclear. In t...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Oncotarget
Prif Awduron: Zheng, Lei, Zhao, Chen, Du, Yuxiang, Lin, Xianchai, Jiang, Yida, Lee, Chunsik, Tian, Geng, Mi, Jia, Li, Xianglin, Chen, Qishan, Ye, Zhimin, Huang, Lijuan, Wang, Shasha, Ren, Xiangrong, Xing, Liying, Chen, Wei, Huang, Delong, Gao, Zhiqin, Zhang, Shuping, Lu, Weisi, Tang, Zhongshu, Wang, Bin, Ju, Rong, Li, Xuri
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Impact Journals LLC 2016
Pynciau:
Research Paper
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5363630/
https://ncbi.nlm.nih.gov/pubmed/27788490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12843
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