Elevated AEG-1 expression in macrophages promotes hypopharyngeal cancer invasion through the STAT3-MMP-9 signaling pathway

Macrophages play a critical role in tumor invasion and metastasis, which remain major causes of mortality in patients with hypopharyngeal cancer. Here we investigate the effect of an oncogene, AEG-1 expressed in macrophages on the invasion of hypopharyngeal cancer cells. AEG-1 is more highly express...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Liu, Xiuxiu, Lv, Zhenghua, Zou, Jidong, Liu, Xianfang, Ma, Juke, Sun, Chengtao, Sa, Na, Xu, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5363584/
https://ncbi.nlm.nih.gov/pubmed/27793010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12886
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