Phosphorylation of PPARγ at Ser84 promotes glycolysis and cell proliferation in hepatocellular carcinoma by targeting PFKFB4

Peroxisome proliferator-activating receptor γ (PPARγ), a transcription factor, is involved in many important biological processes, including cell terminal differentiation, survival and apoptosis. However, the role of PPARγ, which regulates tumour promoter and oncogene expression, is not well underst...

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Vydáno v:Oncotarget
Hlavní autoři: Shu, Yuxin, Lu, Yan, Pang, Xiaojuan, Zheng, Wei, Huang, Yahong, Li, Jiahong, Ji, Jianguo, Zhang, Can, Shen, Pingping
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2016
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5363564/
https://ncbi.nlm.nih.gov/pubmed/27769068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12764
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