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Complement inhibitor CSMD1 acts as tumor suppressor in human breast cancer

Human CUB and Sushi multiple domains 1 (CSMD1) is a membrane-bound complement inhibitor suggested to act as a putative tumor suppressor gene, since allelic loss of this region encompassing 8p23 including CSMD1 characterizes various malignancies. Here, we assessed the role of CSMD1 as a tumor suppres...

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Publicat a:Oncotarget
Autors principals: Escudero-Esparza, Astrid, Bartoschek, Michael, Gialeli, Chrysostomi, Okroj, Marcin, Owen, Sioned, Jirström, Karin, Orimo, Akira, Jiang, Wen G., Pietras, Kristian, Blom, Anna M.
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5363559/
https://ncbi.nlm.nih.gov/pubmed/27764775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12729
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