MicroRNA-22 negatively regulates poly(I:C)-triggered type I interferon and inflammatory cytokine production via targeting mitochondrial antiviral signaling protein (MAVS)

MicroRNAs (miRNAs) are small non-coding RNAs that play important roles in regulating the host immune response. Here we found that miR-22 is induced in glial cells upon stimulation with poly(I:C). Overexpression of miR-22 in the cultured cells resulted in decreased activity of interferon regulatory f...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Wan, Shengfeng, Ashraf, Usama, Ye, Jing, Duan, Xiaodong, Zohaib, Ali, Wang, Wentao, Chen, Zheng, Zhu, Bibo, Li, Yunchuan, Chen, Huanchun, Cao, Shengbo
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5363539/
https://ncbi.nlm.nih.gov/pubmed/27705941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12395
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