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Effect of cobalt-mediated Toll-like receptor 4 activation on inflammatory responses in endothelial cells

Cobalt-containing metal-on-metal hip replacements are associated with adverse reactions to metal debris (ARMD), including inflammatory pseudotumours, osteolysis, and aseptic implant loosening. The exact cellular and molecular mechanisms leading to these responses are unknown. Cobaltions (Co(2+)) act...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Anjum, Sami A., Lawrence, Helen, Holland, James P., Kirby, John A., Deehan, David J., Tyson, Alison J.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5363524/
https://ncbi.nlm.nih.gov/pubmed/27835611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13260
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