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Proteomic differences in brain vessels of Alzheimer’s disease mice: Normalization by PPARγ agonist pioglitazone

Cerebrovascular insufficiency appears years prior to clinical symptoms in Alzheimer’s disease. The soluble, highly toxic amyloid-β species, generated from the amyloidogenic processing of amyloid precursor protein, are known instigators of the chronic cerebrovascular insufficiency observed in both Al...

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Bibliografski detalji
Izdano u:J Cereb Blood Flow Metab
Glavni autori: Badhwar, AmanPreet, Brown, Rebecca, Stanimirovic, Danica B, Haqqani, Arsalan S, Hamel, Edith
Format: Artigo
Jezik:Inglês
Izdano: SAGE Publications 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5363486/
https://ncbi.nlm.nih.gov/pubmed/27339263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0271678X16655172
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