Activation of the ATF6 branch of the unfolded protein response in neurons improves stroke outcome

Impaired function of the endoplasmic reticulum (ER stress) is a hallmark of many human diseases including stroke. To restore ER function in stressed cells, the unfolded protein response (UPR) is induced, which activates 3 ER stress sensor proteins including activating transcription factor 6 (ATF6)....

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Detalhes bibliográficos
Publicado no:J Cereb Blood Flow Metab
Main Authors: Yu, Zhui, Sheng, Huaxin, Liu, Shuai, Zhao, Shengli, Glembotski, Christopher C, Warner, David S, Paschen, Wulf, Yang, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2016
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5363481/
https://ncbi.nlm.nih.gov/pubmed/27217380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0271678X16650218
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