PET radiotracer development for imaging high-affinity state of dopamine D2 and D3 receptors: Binding studies of fluorine-18 labeled aminotetralins in rodents

Imaging the high-affinity, functional state (HA) of dopamine D2 and D3 receptors has been pursued in PET imaging studies of various brain functions. We report further evaluation of (18)F-5-OH-FPPAT, and the newer (18)F-5-OH-FHXPAT and (18)F-7-OH-FHXPAT. Syntheses of (18)F-5-OH-FHXPAT and (18)F-7-OH-...

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Publicado no:Synapse
Main Authors: Mukherjee, Jogeshwar, Majji, Divya, Kaur, Jasmeet, Constantinescu, Cristian C., Narayanan, Tanjore K., Shi, Bingzhi, Nour, Mohamed T., Pan, Min-Liang
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5363407/
https://ncbi.nlm.nih.gov/pubmed/27864853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/syn.21950
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