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Efficient Presentation of Multiple Endogenous Epitopes to Both CD4(+) and CD8(+) Diabetogenic T Cells for Tolerance
Antigen-specific immunotherapy of type 1 diabetes, typically via delivery of a single native β cell antigen, has had little clinical benefit to date. With increasing evidence that diabetogenic T cells react against multiple β cell antigens, including previously unappreciated neo-antigens that can be...
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| Publicado en: | Mol Ther Methods Clin Dev |
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| Autores principales: | , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society of Gene & Cell Therapy
2016
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5363322/ https://ncbi.nlm.nih.gov/pubmed/28344989 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtm.2016.12.002 |
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