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Influence of translation efficiency of homologous viral proteins on the endogenous presentation of CD8(+) T cell epitopes

A significant proportion of endogenously processed CD8(+) T cell epitopes are derived from newly synthesized proteins and rapidly degrading polypeptides (RDPs). It has been hypothesized that the generation of rapidly degrading polypeptides and CD8(+) T cell epitopes from these RDP precursors may be...

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Detalhes bibliográficos
Main Authors: Tellam, Judy, Fogg, Mark H., Rist, Michael, Connolly, Geoff, Tscharke, David, Webb, Natasha, Heslop, Lea, Wang, Fred, Khanna, Rajiv
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2137904/
https://ncbi.nlm.nih.gov/pubmed/17312009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20062508
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