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Quantitative PET Reporter Gene Imaging with [(11)C]Trimethoprim

There is a need for improved methods to image genetically engineered cells, including immune cells used for cell-based therapy. Given the genetic manipulation inherent to gene therapy, the use of a reporter protein is a logical solution and positron emission tomography (PET) can provide the desired...

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Detalhes bibliográficos
Publicado no:Mol Ther
Main Authors: Sellmyer, Mark A., Lee, Iljung, Hou, Catherine, Lieberman, Brian P., Zeng, Chenbo, Mankoff, David A., Mach, Robert H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5363299/
https://ncbi.nlm.nih.gov/pubmed/28129108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2016.10.018
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