DNA Product Formation in Female Sprague–Dawley Rats Following Polyhalogenated Aromatic Hydrocarbon (PHAH) Exposure

[Image: see text] DNA oxidation damage has been regarded as one of the possible mechanisms for the hepatic carcinogenesis of dioxin-like compounds (DLCs). In this study, we evaluated the toxic equivalency factor (TEF) from the standpoint of induced DNA oxidation products and their relationship to to...

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Detalhes bibliográficos
Publicado no:Chem Res Toxicol
Main Authors: Gao, Lina, Mutlu, Esra, Collins, Leonard B., Walker, Nigel J., Hartwell, Hadley J., Olson, James R., Sun, Wei, Gold, Avram, Ball, Louise M., Swenberg, James A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2017
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5363288/
https://ncbi.nlm.nih.gov/pubmed/28207250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.chemrestox.6b00368
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