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Positional Enrichment by Proton Analysis (PEPA): A One‐Dimensional (1)H‐NMR Approach for (13)C Stable Isotope Tracer Studies in Metabolomics
A novel metabolomics approach for NMR‐based stable isotope tracer studies called PEPA is presented, and its performance validated using human cancer cells. PEPA detects the position of carbon label in isotopically enriched metabolites and quantifies fractional enrichment by indirect determination of...
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| Publicado no: | Angew Chem Int Ed Engl |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5363230/ https://ncbi.nlm.nih.gov/pubmed/28220994 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201611347 |
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