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GAL4 transcription factor is not a "zinc finger" but forms a Zn(II)2Cys6 binuclear cluster.

The DNA-binding domain of the transcription factor GAL4, consisting of the 62 N-terminal residues and denoted GAL4(62*), contains a Cys-Xaa2-Cys-Xaa6-Cys-Xaa6-Cys-Xaa2-Cys-Xaa6+ ++-Cys motif, which has been shown previously to bind two Zn(II) or Cd(II) ions. Binding of Zn(II) or Cd(II) is essential...

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Detalhes bibliográficos
Main Authors: Pan, T, Coleman, J E
Formato: Artigo
Idioma:Inglês
Publicado em: 1990
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC53629/
https://ncbi.nlm.nih.gov/pubmed/2107541
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