Clinical Impact of Single Nucleotide Polymorphism in PD-L1 on Response to Nivolumab for Advanced Non-Small-Cell Lung Cancer Patients

This study was intended to determine the efficacy of nivolumab, we evaluated treatment response with respect to PD-1/PD-L1 SNPs among patients with NSCLC. A total of 50 patients with NSCLC were treated with nivolumab and were also evaluated for PD-1/PD-L1 single nucleotide polymorphisms (SNPs) from...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Nomizo, Takashi, Ozasa, Hiroaki, Tsuji, Takahiro, Funazo, Tomoko, Yasuda, Yuto, Yoshida, Hironori, Yagi, Yoshitaka, Sakamori, Yuichi, Nagai, Hiroki, Hirai, Toyohiro, Kim, Young Hak
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2017
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5362817/
https://ncbi.nlm.nih.gov/pubmed/28332580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep45124
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