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Improved lysis efficiency and immunogenicity of Salmonella ghosts mediated by co-expression of λ phage holin-endolysin and ɸX174 gene E

Bacterial ghosts (BGs) are empty cell envelopes derived from Gram-negative bacteria by bacteriophage ɸX174 gene E mediated lysis. They represent a novel inactivated vaccine platform; however, the practical application of BGs for human vaccines seems to be limited due to the safety concerns on the pr...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Won, Gayeon, Hajam, Irshad Ahmed, Lee, John Hwa
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5362813/
https://ncbi.nlm.nih.gov/pubmed/28332591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep45139
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