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Accounting for an isobaric interference allows correct determination of folate vitamers in serum by isotope dilution-liquid chromatography-tandem mass spectrometry(, , )

Mild and prolonged oxidative degradation of 5-methyltetrahydrofolate (5-methylTHF) leads to the biologically inactive pyrazino-s-triazine derivative of 4α-hydroxy-5-methylTHF (MeFox). MeFox and the biologically active 5-formyltetrahydrofolate (5-formylTHF) are isobaric compounds that behave similarl...

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Detalhes bibliográficos
Publicado no:J Nutr
Main Authors: Fazili, Zia, Pfeiffer, Christine M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5362735/
https://ncbi.nlm.nih.gov/pubmed/23173171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3945/jn.112.166769
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