Preservation of Antigen-Specific Functions of αβ T Cells and B Cells Removed from Hematopoietic Stem Cell Transplants Suggests Their Use As an Alternative Cell Source for Advanced Manipulation and Adoptive Immunotherapy

Hematopoietic stem cell transplantation is standard therapy for numerous hematological diseases. The use of haploidentical donors, sharing half of the HLA alleles with the recipient, has facilitated the use of this procedure as patients can rely on availability of a haploidentical donor within their...

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Veröffentlicht in:Front Immunol
Hauptverfasser: Li Pira, Giuseppina, Di Cecca, Stefano, Biagini, Simone, Girolami, Elia, Cicchetti, Elisabetta, Bertaina, Valentina, Quintarelli, Concetta, Caruana, Ignazio, Lucarelli, Barbarella, Merli, Pietro, Pagliara, Daria, Brescia, Letizia Pomponia, Bertaina, Alice, Montanari, Mauro, Locatelli, Franco
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2017
Schlagworte:
Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5362590/
https://ncbi.nlm.nih.gov/pubmed/28386262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00332
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