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What roles do colon stem cells and gap junctions play in the left and right location of origin of colorectal cancers?

This “Commentary” examines an important clinical observation that right-sided colorectal cancers appear less treatable than the left-sided cancers. The concepts of (a) the “initiation/promotion/progression” process, (b) the stem cell hypothesis, (c) the role gap junctional intercellular communicatio...

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Bibliographic Details
Published in:J Cell Commun Signal
Main Authors: Trosko, James E., Lenz, Heinz-Josef
Format: Artigo
Language:Inglês
Published: Springer Netherlands 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5362582/
https://ncbi.nlm.nih.gov/pubmed/28220297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12079-017-0381-y
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