Liver X receptors agonist GW3965 re-sensitizes gefitinib-resistant human non-small cell lung cancer cell to gefitinib treatment by inhibiting NF-κB in vitro

The recent research shows that the inhibition of the nuclear factor-κB (NF-κB) pathway is a promising therapeutic option for patients who progress after treatment with the novel mutant-selective EGFR-TKIs. For propose to find a nontoxic drug to reverse the acquired gefitinib resistance, we examined...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Hu, Yong, Zang, Jialan, Cao, Haixia, Wu, Ying, Yan, Dali, Qin, Xiaobing, Zhou, Leilei, Fan, Fan, Ni, Jie, Xu, Xiaoyue, Sha, Huanhuan, Liu, Siwen, Yu, Shaorong, Wang, Zhuo, Ma, Rong, Wu, Jianzhong, Feng, Jifeng
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5362524/
https://ncbi.nlm.nih.gov/pubmed/28178657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.15007
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