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Up-regulation of tumor suppressor genes by exogenous dhC16-Cer contributes to its anti-cancer activity in primary effusion lymphoma

Primary effusion lymphoma (PEL) is a rare and highly aggressive B-cell malignancy with Kaposi's sarcoma-associated herpesvirus (KSHV) infection, while lack of effective therapies. Our recent data indicated that targeting the sphingolipid metabolism by either sphingosine kinase inhibitor or exog...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Oncotarget
Hauptverfasser: Cao, Yueyu, Qiao, Jing, Lin, Zhen, Zabaleta, Jovanny, Dai, Lu, Qin, Zhiqiang
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5362481/
https://ncbi.nlm.nih.gov/pubmed/28146424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14838
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