Nuclear PRMT5, cyclin D1 and IL-6 are associated with poor outcome in oropharyngeal squamous cell carcinoma patients and is inversely associated with p16-status

Protein arginine methyltransferase-5 (PRMT5) plays an important role in cancer progression by repressing the expression of key tumor suppressor genes via the methylation of transcriptional factors and chromatin-associated proteins. However, very little is known about the expression and biological ro...

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Udgivet i:Oncotarget
Main Authors: Kumar, Bhavna, Yadav, Arti, Brown, Nicole V., Zhao, Songzhu, Cipolla, Michael J., Wakely, Paul E., Schmitt, Alessandra C., Baiocchi, Robert A., Teknos, Theodoros N., Old, Matthew, Kumar, Pawan
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2017
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5362449/
https://ncbi.nlm.nih.gov/pubmed/28107179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14682
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