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AMPK-autophagy inhibition sensitizes icaritin-induced anti-colorectal cancer cell activity

The current research studied the potential effect of autophagy on icaritin-induced anti-colorectal cancer (CRC) cell activity. Treatment of icaritin in both primary and established (HT-29) CRC cells induced feedback activation of autophagy, evidenced by p62 degradation, Beclin-1 and autophagy-relate...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Zhou, Chunxian, Gu, Jun, Zhang, Gang, Dong, Da, Yang, Qunying, Chen, Min-Bin, Xu, Dongfeng
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5362439/
https://ncbi.nlm.nih.gov/pubmed/28103582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14718
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