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NEW DRUG DEVELOPMENTS IN PSYCHOSIS: CHALLENGES, OPPORTUNITIES AND STRATEGIES

All currently approved drugs for schizophrenia work mainly by dopaminergic antagonism. While they are efficacious for psychotic symptoms, their efficacy is limited for negative symptoms and cognitive deficits which underlie the substantive disability in this illness. Recent insights into the biologi...

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Detalhes bibliográficos
Publicado no:Prog Neurobiol
Main Authors: Keshavan, Matcheri S., Lawler, Ashley N., Nasrallah, Henry A., Tandon, Rajiv
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5362348/
https://ncbi.nlm.nih.gov/pubmed/27519538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pneurobio.2016.07.004
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