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AKAP-mediated feedback control of cAMP gradients in developing hippocampal neurons

Cyclic AMP (cAMP) and protein kinase A (PKA), classical examples of spatially compartmentalized signaling molecules, are critical axon determinants that regulate neuronal polarity and axon formation, yet little is known about micro-compartmentalization of cAMP and PKA signaling and its role in devel...

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Bibliografiska uppgifter
I publikationen:Nat Chem Biol
Huvudupphovsmän: Gorshkov, Kirill, Mehta, Sohum, Ramamurthy, Santosh, Ronnett, Gabriele V., Zhou, Feng-Quan, Zhang, Jin
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2017
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5362298/
https://ncbi.nlm.nih.gov/pubmed/28192412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.2298
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