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Electrostatic anchoring precedes stable membrane attachment of SNAP25/SNAP23 to the plasma membrane

The SNAREs SNAP25 and SNAP23 are proteins that are initially cytosolic after translation, but then become stably attached to the cell membrane through palmitoylation of cysteine residues. For palmitoylation to occur, membrane association is a prerequisite, but it is unclear which motif may increase...

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Publicat a:eLife
Autors principals: Weber, Pascal, Batoulis, Helena, Rink, Kerstin M, Dahlhoff, Stefan, Pinkwart, Kerstin, Söllner, Thomas H, Lang, Thorsten
Format: Artigo
Idioma:Inglês
Publicat: eLife Sciences Publications, Ltd 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5362264/
https://ncbi.nlm.nih.gov/pubmed/28240595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.19394
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