SRC-2-mediated coactivation of anti-tumorigenic target genes suppresses MYC-induced liver cancer

Hepatocellular carcinoma (HCC) is the fifth most common solid tumor in the world and the third leading cause of cancer-associated deaths. A Sleeping Beauty-mediated transposon mutagenesis screen previously identified mutations that cooperate with MYC to accelerate liver tumorigenesis. This revealed...

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Udgivet i:PLoS Genet
Main Authors: Suresh, Shruthy, Durakoglugil, Deniz, Zhou, Xiaorong, Zhu, Bokai, Comerford, Sarah A., Xing, Chao, Xie, Xian-Jin, York, Brian, O’Donnell, Kathryn A.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2017
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5362238/
https://ncbi.nlm.nih.gov/pubmed/28273073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006650
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