Uniform FDG-PET guided GRAdient Dose prEscription to reduce late Radiation Toxicity (UPGRADE-RT): study protocol for a randomized clinical trial with dose reduction to the elective neck in head and neck squamous cell carcinoma

BACKGROUND: In definitive radiation therapy for head and neck cancer, clinically uninvolved cervical lymph nodes are irradiated with a so-called ‘elective dose’ in order to achieve control of clinically occult metastases. As a consequence of high-resolution diagnostic imaging, occult tumor volume ha...

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Bibliografische gegevens
Gepubliceerd in:BMC Cancer
Hoofdauteurs: van den Bosch, Sven, Dijkema, Tim, Kunze-Busch, Martina C., Terhaard, Chris H. J., Raaijmakers, Cornelis P. J., Doornaert, Patricia A. H., Hoebers, Frank J. P., Vergeer, Marije R., Kreike, Bas, Wijers, Oda B., Oyen, Wim J. G., Kaanders, Johannes H. A. M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2017
Onderwerpen:
Study Protocol
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5361684/
https://ncbi.nlm.nih.gov/pubmed/28327089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-017-3195-7
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