CDKN2A/p16INK4(a) expression is associated with vascular progeria in chronic kidney disease

Patients with chronic kidney disease (CKD) display a progeric vascular phenotype linked to apoptosis, cellular senescence and osteogenic transformation. This has proven intractable to modelling appropriately in model organisms. We have therefore investigated this directly in man, using for the first...

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Detalhes bibliográficos
Publicado no:Aging (Albany NY)
Main Authors: Stenvinkel, Peter, Luttropp, Karin, McGuinness, Dagmara, Witasp, Anna, Rashid Qureshi, Abdul, Wernerson, Annika, Nordfors, Louise, Schalling, Martin, Ripsweden, Jonaz, Wennberg, Lars, Söderberg, Magnus, Bárány, Peter, Olauson, Hannes, Shiels, Paul G
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5361677/
https://ncbi.nlm.nih.gov/pubmed/28192277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.101173
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