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The molecular mechanism of Atg13 function in autophagy induction: What is hidden behind the data?
Atg13 is an essential subunit of the Atg1 autophagy initiation complex in yeast and its mammalian counterpart, ATG13, is indispensable for autophagy induction by the ULK1 complex. The N terminus of the protein folds into a HORMA domain, an architecture that has been revealed by crystallography.(1-4)...
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| Veröffentlicht in: | Autophagy |
|---|---|
| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Taylor & Francis
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5361603/ https://ncbi.nlm.nih.gov/pubmed/28118060 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2016.1277312 |
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