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Novel PEGylated Basal Insulin LY2605541 Has a Preferential Hepatic Effect on Glucose Metabolism
The impact of the novel basal insulin LY2605541 (LY) on hepatic and nonhepatic glucose uptake (non-HGU) was evaluated. Conscious dogs underwent euglycemic clamps with tracer and hepatic balance measurements. Clamp period infusions were peripheral venous regular insulin (0.1 nmol ⋅ kg(−1) ⋅ h(−1) [co...
Shranjeno v:
| izdano v: | Diabetes |
|---|---|
| Main Authors: | , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Diabetes Association
2014
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5361402/ https://ncbi.nlm.nih.gov/pubmed/24089512 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db13-0826 |
| Oznake: |
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