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Molecular signaling underlying bulleyaconitine A (BAA)-induced microglial expression of prodynorphin
Bulleyaconitine (BAA) has been shown to possess antinociceptive activities by stimulation of dynorphin A release from spinal microglia. This study investigated its underlying signal transduction mechanisms. The data showed that (1) BAA treatment induced phosphorylation of CREB (rather than NF-κB) an...
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| Pubblicato in: | Sci Rep |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5361206/ https://ncbi.nlm.nih.gov/pubmed/28327597 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep45056 |
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