Andrographolide Activates Keap1/Nrf2/ARE/HO-1 Pathway in HT22 Cells and Suppresses Microglial Activation by Aβ(42) through Nrf2-Related Inflammatory Response

Therapeutic approach of Alzheimer's disease (AD) has been gradually diversified. We examined the therapeutic and preventive potential of andrographolide, which is a lactone diterpenoid from Andrographis paniculata, and focused on the Kelch-like ECH-associated protein 1 (Keap1)/nuclear factor (e...

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Bibliografiske detaljer
Udgivet i:Mediators Inflamm
Main Authors: Seo, Ji Yeon, Pyo, Euisun, An, Jin-Pyo, Kim, Jinwoong, Sung, Sang Hyun, Oh, Won Keun
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi 2017
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5360972/
https://ncbi.nlm.nih.gov/pubmed/28373747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/5906189
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