Galactosylation and Sialylation Levels of IgG Predict Relapse in Patients With PR3-ANCA Associated Vasculitis

OBJECTIVE: The objective of our study is to investigate the Fc glycosylation profiles of both antigen-specific IgG targeted against proteinase 3 (PR3-ANCA) and total IgG as prognostic markers of relapse in patients with Granulomatosis with Polyangiitis (GPA). METHODS: Seventy-five patients with GPA...

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Bibliografiske detaljer
Udgivet i:EBioMedicine
Main Authors: Kemna, Michael J., Plomp, Rosina, van Paassen, Pieter, Koeleman, Carolien A.M., Jansen, Bas C., Damoiseaux, Jan G.M.C., Cohen Tervaert, Jan Willem, Wuhrer, Manfred
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2017
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5360573/
https://ncbi.nlm.nih.gov/pubmed/28169190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2017.01.033
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