Extracorporeal IgE Immunoadsorption in Allergic Asthma: Safety and Efficacy

BACKGROUND: Prevention of IgE-binding to cellular IgE-receptors by anti-IgE (Omalizumab) is clinically effective in allergic asthma, but limited by IgE threshold-levels. To overcome this limitation, we developed a single-use IgE immunoadsorber column (IgEnio). IgEnio is based on a recombinant, IgE-s...

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Publicado en:EBioMedicine
Main Authors: Lupinek, Christian, Derfler, Kurt, Lee, Silvia, Prikoszovich, Thomas, Movadat, Oliver, Wollmann, Eva, Cornelius, Carolin, Weber, Milena, Fröschl, Renate, Selb, Regina, Blatt, Katharina, Smiljkovic, Dubravka, Schoder, Volker, Cervenka, René, Plaichner, Thomas, Stegfellner, Gottfried, Huber, Hans, Henning, Rainer, Kozik-Jaromin, Justyna, Perkmann, Thomas, Niederberger, Verena, Petkov, Ventzislav, Valent, Peter, Gauly, Adelheid, Leinenbach, Hans Peter, Uhlenbusch-Koerwer, Ingrid, Valenta, Rudolf
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2017
Assuntos:
Research Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5360571/
https://ncbi.nlm.nih.gov/pubmed/28254561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2017.02.007
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