Whole Exome Sequencing Reveals Severe Thrombophilia in Acute Unprovoked Idiopathic Fatal Pulmonary Embolism

BACKGROUND: Acute unprovoked idiopathic fatal pulmonary embolism (IFPE) causes sudden death without an identifiable thrombogenic risk. We aimed to investigate the underlying genomic risks of IFPE through whole exome sequencing (WES). METHODS: We reviewed 14 years of consecutive out-of-hospital fatal...

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Bibliografski detalji
Izdano u:EBioMedicine
Glavni autori: Halvorsen, Matt, Lin, Ying, Sampson, Barbara A., Wang, Dawei, Zhou, Bo, Eng, Lucy S., Um, Sung Yon, Devinsky, Orrin, Goldstein, David B., Tang, Yingying
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2017
Teme:
Research Paper
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5360570/
https://ncbi.nlm.nih.gov/pubmed/28174134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2017.01.037
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