Treatment of multiple myeloma with monoclonal antibodies and the dilemma of false positive M-spikes in peripheral blood

OBJECTIVES: To characterize the effect of three humanized IgG κ monoclonal antibodies (daratumumab, isatuximab, and elotuzumab) on the interpretation of results generated by protein electrophoresis, immunofixation, free light chain, and heavy/light chain assays performed on human serum. METHODS: Hea...

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Udgivet i:Clin Biochem
Main Authors: Murata, Kazunori, McCash, Samuel I, Carroll, Brittany, Lesokhin, Alexander M, Hassoun, Hani, Lendvai, Nikoletta, Korde, Neha S, Mailankody, Sham, Landau, Heather J, Koehne, Guenther, Chung, David J, Giralt, Sergio A, Ramanathan, Lakshmi V, Landgren, Ola
Format: Artigo
Sprog:Inglês
Udgivet: 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5360528/
https://ncbi.nlm.nih.gov/pubmed/27664535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clinbiochem.2016.09.015
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