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Local TNFR1 signaling licenses murine neutrophils for increased TLR-dependent cytokine and eicosanoid production

Neutrophils are generally the first immune cells recruited during the development of sterile or microbial inflammation. As these cells express many innate immune receptors with the potential to directly recognize microbial or endogenous signals, we set out to assess whether their functions are local...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Deguine, Jacques, Wei, Jessica, Barbalat, Roman, Gronert, Karsten, Barton, Gregory M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5360520/
https://ncbi.nlm.nih.gov/pubmed/28219890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1601465
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