A mutagenesis-derived Lrp5 mouse mutant with abnormal retinal vasculature and low bone mineral density

PURPOSE: Familial exudative vitreoretinopathy (FEVR) is caused by mutations in the genes encoding low-density lipoprotein receptor-related protein (LRP5) or its interacting partners, namely frizzled class receptor 4 (FZD4) and norrin cystine knot growth factor (NDP). Mouse models for Lrp5, Fzd4, and...

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發表在:Mol Vis
Main Authors: Charette, Jeremy R., Earp, Sarah E., Bell, Brent A., Ackert-Bicknell, Cheryl L., Godfrey, Dana A., Rao, Sujata, Anand-Apte, Bela, Nishina, Patsy M., Peachey, Neal S.
格式: Artigo
語言:Inglês
出版: Molecular Vision 2017
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Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5360454/
https://ncbi.nlm.nih.gov/pubmed/28356706
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