Angiopep-2-conjugated poly(ethylene glycol)-co- poly(ε-caprolactone) polymersomes for dual-targeting drug delivery to glioma in rats

The blood–brain barrier is a formidable obstacle for glioma chemotherapy due to its compact structure and drug efflux ability. In this study, a dual-targeting drug delivery system involving Angiopep-2-conjugated biodegradable polymersomes loaded with doxorubicin (Ang-PS-DOX) was developed to exploit...

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Dettagli Bibliografici
Pubblicato in:Int J Nanomedicine
Autori principali: Lu, Fei, Pang, Zhiyong, Zhao, Jingjing, Jin, Kai, Li, Haichun, Pang, Qiang, Zhang, Long, Pang, Zhiqing
Natura: Artigo
Lingua:Inglês
Pubblicazione: Dove Medical Press 2017
Soggetti:
Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5360408/
https://ncbi.nlm.nih.gov/pubmed/28356732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S123422
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